Recent studies show that the famous gene-editing tool does more in bacteria than just spot DNA for chopping up; it coordinates with other proteins to bulk up defenses against invading viruses as well.
Now scientists have used CRISPR to remove and add genes to these cells to help them recognize a patient’s specific tumor cells.
For the first time in the world, complete chromosomal rearrangement in mammals have been achieved, making a new breakthrough in synthetic biology.
A genetic mutation that a Chinese scientist attempted to create in twin babies born last year, ostensibly to help them fend off HIV infection, is also associated with a 21% increase in mortality in later life.
Scientists have discovered a new technique that can leave out particular sections of a gene, essentially 'skipping' them. New method, called CRISPR-SKIP, could be used to control how genes are expressed and regulated.
Researchers have developed a new platform that makes CRISPR less like a cutting tool and more like a word processor with a search-and-replace function.
Editing another essential molecular component of our biology—RNA, the messenger used by cells to turns DNA instructions into proteins— holds great promise.
In the U.S., the first planned clinical trials of CRISPR gene editing in people are about to kick off. China already used the gene-altering tool to change the DNA of dozens of people in several clinical trials.
To avoid off-target mutations, scientists at the Salk Institute modified CRISPR to become a gene activator instead of a gene editor.
US scientists have edited the DNA inside of a patient’s body, in an attempt to cure a genetic disorder by permanently changing the human genome. The news represents a major landmark in science.
Scientists have, for the first time, corrected a disease-causing mutation in early stage human embryos with gene editing.
The data is unpublished, but scientists say it advances effort to erase genetic diseases.
A new study offers a cautionary tale for using the widely hyped gene-editing tool CRISPR on people.