CRISPR baby mutation significantly increases mortality

A genetic mutation that a Chinese scientist attempted to create in twin babies born last year, ostensibly to help them fend off HIV infection, is also associated with a 21% increase in mortality in later life.

A biosynthetic dual-core cell computer

Swiss researchers have now found a way to use biological components to construct a flexible core processor, that accepts different kinds of programming. The processor developed is based on a modified CRISPR-Cas9 system.

New CRISPR Method That 'Skips' Over Gene Sections

Scientists have discovered a new technique that can leave out particular sections of a gene, essentially 'skipping' them. New method, called CRISPR-SKIP, could be used to control how genes are expressed and regulated.

New platform transforms gene editor into precision tool

Researchers have developed a new platform that makes CRISPR less like a cutting tool and more like a word processor with a search-and-replace function.

How Editing RNA—Not DNA—Could Cure Disease in the Future

Editing another essential molecular component of our biology—RNA, the messenger used by cells to turns DNA instructions into proteins— holds great promise.

China Has Already Gene-Edited 86 People With CRISPR

In the U.S., the first planned clinical trials of CRISPR gene editing in people are about to kick off. China already used the gene-altering tool to change the DNA of dozens of people in several clinical trials.

‘No-Cut’ CRISPR Activates Genes Without Altering DNA

To avoid off-target mutations, scientists at the Salk Institute modified CRISPR to become a gene activator instead of a gene editor.

In a Major First, Scientists Edit DNA Within the Human Body

US scientists have edited the DNA inside of a patient’s body, in an attempt to cure a genetic disorder by permanently changing the human genome. The news represents a major landmark in science.

Gene-editing success holds promise for preventing inherited diseases

Scientists have, for the first time, corrected a disease-causing mutation in early stage human embryos with gene editing.

Human embryo edited for first time in US, pushes limits

The data is unpublished, but scientists say it advances effort to erase genetic diseases.

CRISPR DNA Editing Can Cause Hundreds of Off-Target Mutations

A new study offers a cautionary tale for using the widely hyped gene-editing tool CRISPR on people.

Gene editing strategy eliminates HIV-1 infection

Scientists have demonstrated that HIV-1 replication can be completely shut down and the virus eliminated from infected cells in animals with a powerful gene editing technology.

CRISPR Pill May Be Key in Fight Against Antibiotic Resistance

Teams of scientists are now working on a truly creative strategy: a pill carrying the genome-editing power tool CRISPR that instructs harmful bacteria to shred their own genes to bits.

Scientists make a viable semi-synthetic organism

The lifeform holds on to its artificial genetic letters without a hitch.

Lung Cancer Patient First to Undergo CRISPR Gene Editing

The CRISPR-Cas9 gene editing technique has been used in its first human trial. Scientists at Sichuan University in Chengdu, China began a trial last month to treat a lung cancer patient.